​2024

• Perez C, Szymanski CM (2024) More than one way to add a sugar into bacterial polysaccharides. Proc. Natl. Acad. Sci. U.S.A. 121(25):e2408556121. doi: 10.1073/pnas.2408556121.

• Barbuti MD, Lambert E, Myrbråten IS, Ducret A, Stamsås GA, Wilhelm L, Liu X, Salehian Z, Veening J-W, Straume D, Grangeasse C, Perez C, Kjos M. (2024) The function of CozE proteins is linked to lipoteichoic acid biosynthesis in Staphylococcus aureus. mBio. doi: 10.1128/mbio.01157-24  

• ​Khare S, Villalba MI, Canul-Tec JC, Balsebre-Cajiao A, Kumar A, Backovic M, Rey FA, Pardon E, Steyaert J, Perez C, Reyes N (2024) Receptor-recognition and antiviral mechanisms of retrovirus-derived human proteins. Nat. Struct. Mol. Biol. doi.org/10.1038/s41594-024-01295-6

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2023

• Degen M, Santos JC, Pluhackova K, Cebrero G, Ramos S, Jankevicius G, Hartenian E, Guillerm U, Mari SA, Kohl B, Müller DJ, Schanda P, Maier T, Perez C, Sieben C, Broz P, Hiller S (2023) Structural basis of NINJ1-mediated plasma membrane rupture in cell death. Nature. 618, pp. 1065–1071.

• Minhas V, Domenech A, Synefiaridou D, Straume D, Brendel M, Cebrero G, Liu X, Costa C, Baldry M, Sirard JC, Perez C, Gisch N, Hammerschmidt S, Håvarstein LS, Veening JW (2023) Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence. PLoS Biology. 21(1), p. e3001990.

• Perez C (2023) How to measure omega-3 fatty acid lysolipid flipping: The ultimate guide. Proc. Natl. Acad. Sci. U.S.A. 120(14), p. e2302321120.

• Barbuti MD, Lambert E, Myrbråten IS, Ducret A, Stamsås GA, Wilhelm L, Liu X, Salehian Z, Veening JW, Straume D, Grangeasse C, Perez C, Kjos M (2023) The function of CozE proteins is linked to lipoteichoic acid biosynthesis in Staphylococcus aureus. bioRxiv 2023.10.20.563254

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2022 ​

• Heinz V, Güler G, Leone V, Madej MG, Maksimov S, Gärtner RM, Rudi O, Hamdi F, Kastritis PL, Mäntele W, Krämer R, Forrest LR, Perez C and Ziegler C (2022) Osmotic stress response in BetP: How lipids and K+ team up to overcome downregulation. bioRxiv 2022.06.02.493408

• Bärland N, Rueff AS, Cebrero G, Hutter CA, Seeger MA, Veening JW, Perez C (2022). Mechanistic basis of choline import involved in teichoic acids and lipopolysaccharide modification. Sci. Adv., 8(9), p. eabm1122.

• Lambert E, Mehdipour AR, Schmidt A, Hummer G, Perez C (2022) Evidence for a trap-and-flip mechanism in a proton-dependent lipid transporter.  Nat. Comm., 13, p. 1022

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2021 

• Bärland N, Perez C (2021) Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane (SSM)-Based Electrophysiology. J. Vis. Exp., 171, e62578, doi: 10.3791/62578 

• Reinders, A., Sellner, B., Fadel, F., van Berkum, M., Kaczmarczyk, A., Ozaki, S., Rueher, J., Manfredi, P., Sangermani, M., Harms, A., Perez, C., Schirmer, T. and Jenal, U. (2021) Digital control of c-di-GMP in E. coli balances population-wide developmental transitions and phage sensitivity. bioRxiv 2021.10.01.462762

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2020 

• Zhang B, Liu X, Lambert L, Mas G, Hiller S, Veening JW, Perez C (2020) Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis. Nat. Struct. Mol. Biol., 27, pp. 561–569.

• Zhang B, Perez C (2020) Stabilization and crystallization of a membrane protein involved in lipid transport. Methods in Mol. Biol. 2127, 283-292 

• Baerland N, Perez C (2020) Fast Small-Scale Membrane Protein Purification and Grid Preparation for Single Particle Electron Microscopy. Methods in Mol. Biol. 2127, 275-282

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2019 

• Perez C*, Mehdipour A*, Hummer G, Locher KP (2019) Structure of outward-facing PglK and molecular dynamics of lipid-linked oligosaccharide recognition and translocation. Structure. 27(4):669-678

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2018

• Köhler M, Neff C, Perez C, Brunner C, Pardon E, Steyaert J, Schneider G, Locher KP, Zenobi R (2018) Binding Specificities of Nanobody center dot Membrane Protein Complexes Obtained from Chemical Cross-Linking and High-Mass MALDI Mass Spectrometry. Analytical Chemistry. doi: 10.1021/acs.analchem.8b00236 

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2017

• Perez C, Köhler M, Janser D, Pardon E, Steyaert J, Zenobi R, Locher KP (2017) Structural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody. Sci. Rep. 7:46641

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2015​

• Perez C, Gerber S, Boilevin J, Bucher M, Darbre T, Aebi M, Reymond JL, Locher KP (2015) Structure and mechanism of an active lipid-linked oligosaccharide flippase. Nature. 524(7566):433-8

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2014​​

• Perez C*, Faust B*, Mehdipour AR*, Francesconi KA, Forrest LR, Ziegler C (2014) Substrate-bound outward open state of the betaine transporter BetP provides insights into Na+ coupling. Nat. Comm. 5: 4231

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2013​

• Koshy C, Schweikhard ES, Gartner RM, Perez C, Yildiz O, Ziegler C (2013) Structural evidence for functional lipid interactions in the betaine transporter BetP. EMBO J. 32: 3096-3105

• Perez C, Ziegler C (2013) Mechanistic aspects of sodium-binding sites in LeuT-like fold symporters. Biol. Chem. 394(5) 641-8

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2012​​

• Perez C*, Koshy C*, Yildis Ö, Ziegler C (2012) Alternating-access mechanism in conformationally asymmetric trimers of the betaine transporter BetP. Nature. 490: 126-30 

• Khafizov K*, Perez C*, Koshy C, Quick M, Fendler K, Ziegler C, Forrest L (2012) Investigation of the sodium binding sites in the sodium-coupled betaine transporter BetP. Proc. Natl. Acad. Sci. U.S.A. 109: E3035-3044 

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2011

• Ge L*, Perez C*, Waclawska I, Ziegler C, Muller DL (2011) Locating an extracellular K+-dependent interaction site that modulates betaine-binding of the Na+-coupled betaine symporter BetP. Proc. Natl. Acad. Sci. U.S.A. 108(43): E890-8 

• Gärtner RM, Perez C, Koshy C, Ziegler C (2011) Role of bundle helices in a regulatory crosstalk in the trimeric betaine transporter BetP. J. Mol. Biol. 414(3): 327-36 

• Perez C, Khafizov K, Forrest LR, Kramer R, Ziegler C (2011) The role of trimerization in the osmoregulated betaine transporter BetP. EMBO Rep. 12: 804-810 

• Perez C, Koshy C, Ressl S, Nicklisch S, Krämer R, Ziegler C (2011) Substrate specificity and ion coupling in the Na+/betaine symporter BetP. EMBO J. 30(7): 1221-9